NFATC3 promotes IRF7 transcriptional activity in plasmacytoid dendritic cells
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چکیده
منابع مشابه
NFATC3 promotes IRF7 transcriptional activity in plasmacytoid dendritic cells
Plasmacytoid dendritic cells (pDCs) rapidly produce large amounts of type 1 interferon (IFN) after Toll-like receptor 7 and 9 engagements. This specialized function of type 1 IFN production is directly linked to the constitutive expression of IRF7, the master transcription factor for type 1 IFN production. However, the IRF7 regulatory network in pDCs remains largely unknown. In this study, we i...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 2016
ISSN: 0022-1007,1540-9538
DOI: 10.1084/jem.20160438